Histomorphological Spectrum of Prostatic Lesions in Yobe State: A Preliminary Report.

Abstract

Introduction: Lesions of the prostate including prostate cancer are globally recognized as common causes of morbidity and mortality in the male population. The incidences are increasing, hence; their implication on the men's quality of life cannot be over emphasized. Objectives: To evaluate the histologic reports of prostatic specimens in some tertiary health institution in Yobe State, Methods: The reports of prostatic specimens that were examined between October 2016 and October 2019 in the two departments of Histopathology of Yobe state University Teaching Hospital (YSUTH) and Federal Medical Centre Nguru were retrospectively evaluated, analyzed using SPSS version 21. Result: A total of 287 specimens were examined, and predominated by the 161 (56.1%) specimens in YSUTH. Nodular hyperplasia with or without associated prostatitis was the common benign lesion in 237 (82.6%) of the specimens. Adenocarcinoma was the only malignant type in 49 (17.1%), commonly in the age group of 70-79yrs. More than half (53.1%) of the malignancies were poorly differentiated. Prostatic Intra-epithelial Neoplasia (PIN) was seen in 0.35% only. Conclusion: Although more benign lesions were observed than malignant, but most of the malignancies were diagnosed late. Hence, there is need to strengthen awareness campaign to allow for early detection of these lesions.